A 2.8 Å Structure of Zoliflodacin in a DNA Cleavage Complex with Staphylococcus aureus DNA Gyrase

Since 2000, some thirteen quinolones and fluoroquinolones have been developed and have come to market. The quinolones, one of the most successful classes of antibacterial drugs, stabilize DNA cleavage complexes with DNA gyrase and topoisomerase IV (topo IV), the two bacterial type IIA topoisomerases...

Descripción completa

Detalles Bibliográficos
Autores principales: Morgan, Harry, Lipka-Lloyd, Magdalena, Warren, Anna J., Hughes, Naomi, Holmes, John, Burton, Nicolas P., Mahenthiralingam, Eshwar, Bax, Ben D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865888/
https://www.ncbi.nlm.nih.gov/pubmed/36675148
http://dx.doi.org/10.3390/ijms24021634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865888/
https://www.ncbi.nlm.nih.gov/pubmed/36675148
http://dx.doi.org/10.3390/ijms24021634

Ejemplares similares