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Improving the Antimycobacterial Drug Clofazimine through Formation of Organic Salts by Combination with Fluoroquinolones

This work reports the synthesis, structural and thermal analysis, and in vitro evaluation of the antimicrobial activity of two new organic salts (OSs) derived from the antimycobacterial drug clofazimine and the fluoroquinolones ofloxacin or norfloxacin. Organic salts derived from active pharmaceutic...

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Detalles Bibliográficos
Autores principales: Bento, Clara M., Silva, Ana Teresa, Mansano, Bruno, Aguiar, Luísa, Teixeira, Cátia, Gomes, Maria Salomé, Gomes, Paula, Silva, Tânia, Ferraz, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865903/
https://www.ncbi.nlm.nih.gov/pubmed/36674923
http://dx.doi.org/10.3390/ijms24021402