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Highly Polymorphic Materials and Dissolution Behaviour: The Peculiar Case of Rifaximin

Rifaximin is a locally acting antibiotic practically insoluble in water. It presents several crystal phases characterized by different degrees of hydration. The aim of this work is to investigate the dissolution behaviour of rifaximin α, β, and amorphous forms in relation to their relative thermodyn...

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Detalles Bibliográficos
Autores principales: Bianchera, Annalisa, Nebuloni, Marino, Colombo, Nicola, Pirola, Davide, Bettini, Ruggero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865978/
https://www.ncbi.nlm.nih.gov/pubmed/36678682
http://dx.doi.org/10.3390/pharmaceutics15010053