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Highly Polymorphic Materials and Dissolution Behaviour: The Peculiar Case of Rifaximin
Rifaximin is a locally acting antibiotic practically insoluble in water. It presents several crystal phases characterized by different degrees of hydration. The aim of this work is to investigate the dissolution behaviour of rifaximin α, β, and amorphous forms in relation to their relative thermodyn...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865978/ https://www.ncbi.nlm.nih.gov/pubmed/36678682 http://dx.doi.org/10.3390/pharmaceutics15010053 |