Design and Characterization of Mutated Variants of the Oncotoxic Parvoviral Protein NS1

Oncotoxic proteins such as the non-structural protein 1 (NS1), a constituent of the rodent parvovirus H1 (H1-PV), offer a novel approach for treatment of tumors that are refractory to other treatments. In the present study, mutated NS1 variants were designed and tested with respect to their oncotoxi...

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Detalles Bibliográficos
Autores principales: Hauswirth, Patrick, Graber, Philipp, Buczak, Katarzyna, Mancuso, Riccardo Vincenzo, Schenk, Susanne Heidi, Nüesch, Jürg P. F., Huwyler, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866090/
https://www.ncbi.nlm.nih.gov/pubmed/36680249
http://dx.doi.org/10.3390/v15010209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866090/
https://www.ncbi.nlm.nih.gov/pubmed/36680249
http://dx.doi.org/10.3390/v15010209

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