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Design and Characterization of Mutated Variants of the Oncotoxic Parvoviral Protein NS1
Oncotoxic proteins such as the non-structural protein 1 (NS1), a constituent of the rodent parvovirus H1 (H1-PV), offer a novel approach for treatment of tumors that are refractory to other treatments. In the present study, mutated NS1 variants were designed and tested with respect to their oncotoxi...
Autores principales: | Hauswirth, Patrick, Graber, Philipp, Buczak, Katarzyna, Mancuso, Riccardo Vincenzo, Schenk, Susanne Heidi, Nüesch, Jürg P. F., Huwyler, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866090/ https://www.ncbi.nlm.nih.gov/pubmed/36680249 http://dx.doi.org/10.3390/v15010209 |
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