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Hybrid Silica-Coated PLGA Nanoparticles for Enhanced Enzyme-Based Therapeutics

Some cancer cells rely heavily on non-essential biomolecules for survival, growth, and proliferation. Enzyme based therapeutics can eliminate these biomolecules, thus specifically targeting neoplastic cells; however, enzyme therapeutics are susceptible to immune clearance, exhibit short half-lives,...

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Detalles Bibliográficos
Autores principales: Gustafson, Kyle T., Mokhtari, Negin, Manalo, Elise C., Montoya Mira, Jose, Gower, Austin, Yeh, Ya-San, Vaidyanathan, Mukanth, Esener, Sadik C., Fischer, Jared M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866096/
https://www.ncbi.nlm.nih.gov/pubmed/36678770
http://dx.doi.org/10.3390/pharmaceutics15010143