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Effect of Esomeprazole Treatment on Extracellular Tumor pH in a Preclinical Model of Prostate Cancer by MRI-CEST Tumor pH Imaging

Novel anticancer treatments target the pH regulating system that plays a major role in tumor progression by creating an acidic microenvironment, although few studies have addressed their effect on tumor acidosis. In this study, we investigated in vivo several proton pump inhibitors (PPIs) targeting...

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Detalles Bibliográficos
Autores principales: Irrera, Pietro, Roberto, Miriam, Consolino, Lorena, Anemone, Annasofia, Villano, Daisy, Navarro-Tableros, Victor, Carella, Antonella, Dastrù, Walter, Aime, Silvio, Longo, Dario Livio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866131/
https://www.ncbi.nlm.nih.gov/pubmed/36676972
http://dx.doi.org/10.3390/metabo13010048