Tailored PGE2 Immunomodulation of moDCs by Nano-Encapsulated EP2/EP4 Antagonists

Prostaglandin E2 (PGE2) is an important maturation mediator for dendritic cells (DCs). However, increased PGE2 levels in the tumor exert immunosuppressive effects on DCs by signaling through two E-Prostanoid (EP) receptors: EP2 and EP4. Blocking EP-receptor signaling of PGE2 with antagonists is curr...

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Detalles Bibliográficos
Autores principales: Bödder, Johanna, Kok, Leanne M., Fauerbach, Jonathan A., Flórez-Grau, Georgina, de Vries, I. Jolanda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866164/
https://www.ncbi.nlm.nih.gov/pubmed/36674907
http://dx.doi.org/10.3390/ijms24021392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866164/
https://www.ncbi.nlm.nih.gov/pubmed/36674907
http://dx.doi.org/10.3390/ijms24021392

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