Long-Circulating and Fusogenic Liposomes Loaded with Paclitaxel and Doxorubicin: Effect of Excipient, Freezing, and Freeze-Drying on Quality Attributes

Liposomes can increase plasma half-life, enhance targeting, and diminish the side-effects of loaded drugs. On the downside, physical and chemical instabilities of dispersions often result in a reduced lifespan, which limits their availability on the market. Solid formulations obtained by freeze-dryi...

Descripción completa

Detalles Bibliográficos
Autores principales: Roque, Marjorie, Geraldes, Danilo, da Silva, Caroline, Oliveira, Mônica, Nascimento, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866235/
https://www.ncbi.nlm.nih.gov/pubmed/36678715
http://dx.doi.org/10.3390/pharmaceutics15010086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866235/
https://www.ncbi.nlm.nih.gov/pubmed/36678715
http://dx.doi.org/10.3390/pharmaceutics15010086

Ejemplares similares