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Long-Circulating and Fusogenic Liposomes Loaded with Paclitaxel and Doxorubicin: Effect of Excipient, Freezing, and Freeze-Drying on Quality Attributes
Liposomes can increase plasma half-life, enhance targeting, and diminish the side-effects of loaded drugs. On the downside, physical and chemical instabilities of dispersions often result in a reduced lifespan, which limits their availability on the market. Solid formulations obtained by freeze-dryi...
Autores principales: | Roque, Marjorie, Geraldes, Danilo, da Silva, Caroline, Oliveira, Mônica, Nascimento, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866235/ https://www.ncbi.nlm.nih.gov/pubmed/36678715 http://dx.doi.org/10.3390/pharmaceutics15010086 |
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