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Selective Depletion of ZAP-Binding CpG Motifs in HCV Evolution

Hepatitis C virus (HCV) is a bloodborne pathogen that can cause chronic liver disease and hepatocellular carcinoma. The loss of CpGs from virus genomes allows escape from restriction by the host zinc-finger antiviral protein (ZAP). The evolution of HCV in the human host has not been explored in the...

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Detalles Bibliográficos
Autores principales: Mukherjee, Sanket, Kumar, Akhil, Samal, Jasmine, Gupta, Ekta, Vivekanandan, Perumal, Menon, Manoj B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866289/
https://www.ncbi.nlm.nih.gov/pubmed/36678391
http://dx.doi.org/10.3390/pathogens12010043