Non-Nucleoside Inhibitors Decrease Foot-and-Mouth Disease Virus Replication by Blocking the Viral 3D(pol)

Foot-and-mouth disease virus (FMDV), an economically important pathogen of cloven-hoofed livestock, is a positive-sense, single-stranded RNA virus classified in the Picornaviridae family. RNA-dependent RNA polymerase (RdRp) of RNA viruses is highly conserved. Compounds that bind to the RdRp active s...

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Detalles Bibliográficos
Autores principales: Theerawatanasirikul, Sirin, Semkum, Ploypailin, Lueangaramkul, Varanya, Chankeeree, Penpitcha, Thangthamniyom, Nattarat, Lekcharoensuk, Porntippa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866314/
https://www.ncbi.nlm.nih.gov/pubmed/36680163
http://dx.doi.org/10.3390/v15010124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866314/
https://www.ncbi.nlm.nih.gov/pubmed/36680163
http://dx.doi.org/10.3390/v15010124

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