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Non-Nucleoside Inhibitors Decrease Foot-and-Mouth Disease Virus Replication by Blocking the Viral 3D(pol)
Foot-and-mouth disease virus (FMDV), an economically important pathogen of cloven-hoofed livestock, is a positive-sense, single-stranded RNA virus classified in the Picornaviridae family. RNA-dependent RNA polymerase (RdRp) of RNA viruses is highly conserved. Compounds that bind to the RdRp active s...
Autores principales: | Theerawatanasirikul, Sirin, Semkum, Ploypailin, Lueangaramkul, Varanya, Chankeeree, Penpitcha, Thangthamniyom, Nattarat, Lekcharoensuk, Porntippa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866314/ https://www.ncbi.nlm.nih.gov/pubmed/36680163 http://dx.doi.org/10.3390/v15010124 |
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