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Prenatal Lipopolysaccharide Exposure Alters Hepatic Drug-Metabolizing Enzyme Expression in Mouse Offspring via Histone Modifications

Inflammation is a major regulator of drug-metabolizing enzymes (DMEs), therefore contributing to the interindividual variability of drug effects. However, whether prenatal inflammation affects DMEs expression in offspring remains obscure. This study investigated the effects of prenatal lipopolysacch...

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Detalles Bibliográficos
Autores principales: Zhu, Hanhan, Liu, Guangming, Chang, Qi, Yan, Mengyao, Yang, Kun, Li, Yanxin, Nie, Yali, Li, Xiaotian, Han, Shengna, Wang, Pei, Zhang, Lirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866336/
https://www.ncbi.nlm.nih.gov/pubmed/36668808
http://dx.doi.org/10.3390/toxics11010082