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In Silico and In Vitro Study of Janus Kinases Inhibitors from Naphthoquinones

Janus kinases (JAKs) are involved in numerous cellular signaling processes related to immune cell functions. JAK2 and JAK3 are associated with the pathogenesis of leukemia and common lymphoid-derived illnesses. JAK2/3 inhibitors could reduce the risk of various diseases by targeting this pathway. He...

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Detalles Bibliográficos
Autores principales: Sanachai, Kamonpan, Mahalapbutr, Panupong, Tabtimmai, Lueacha, Seetaha, Supaphorn, Kaekratoke, Nantawat, Chamni, Supakarn, Azam, Syed Sikander, Choowongkomon, Kiattawee, Rungrotmongkol, Thanyada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866339/
https://www.ncbi.nlm.nih.gov/pubmed/36677654
http://dx.doi.org/10.3390/molecules28020597