α-Synuclein Aggregates in the Nigro-Striatal Dopaminergic Pathway Impair Fine Movement: Partial Reversal by the Adenosine A(2A) Receptor Antagonist

Parkinson’s disease (PD) is characterized pathologically by abnormal aggregation of alpha-synuclein (α-Syn) in the brain and clinically by fine movement deficits at the early stage, but the roles of α-Syn and associated neural circuits and neuromodulator bases in the development of fine movement def...

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Detalles Bibliográficos
Autores principales: Cai, Qionghui, Xu, Na, He, Yan, Zhu, Jiamin, Ye, Fenfen, Luo, Zhi, Lu, Ruojun, Huang, Linshan, Zhang, Feiyang, Chen, Jiang-Fan, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866360/
https://www.ncbi.nlm.nih.gov/pubmed/36674880
http://dx.doi.org/10.3390/ijms24021365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866360/
https://www.ncbi.nlm.nih.gov/pubmed/36674880
http://dx.doi.org/10.3390/ijms24021365

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