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The Anti-Tubercular Aminolipopeptide Trichoderin A Displays Selective Toxicity against Human Pancreatic Ductal Adenocarcinoma Cells Cultured under Glucose Starvation

Pancreatic ductal adenocarcinoma remains a highly debilitating condition with no effective disease-modifying interventions. In our search for natural products with promising anticancer activity, we identified the aminolipopeptide trichoderin A as a potential candidate. While it was initially isolate...

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Detalles Bibliográficos
Autores principales: Kasim, Johanes K., Hong, Jiwon, Hickey, Anthony J. R., Phillips, Anthony R. J., Windsor, John A., Harris, Paul W. R., Brimble, Margaret A., Kavianinia, Iman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866366/
https://www.ncbi.nlm.nih.gov/pubmed/36678914
http://dx.doi.org/10.3390/pharmaceutics15010287