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Evaluation of pH-Sensitive Polymeric Micelles Using Citraconic Amide Bonds for the Co-Delivery of Paclitaxel, Etoposide, and Rapamycin

Paclitaxel (PTX), etoposide (ETP), and rapamycin (RAPA) have different mechanisms, allowing multiple pathways to be targeted simultaneously, effectively treating various cancers. However, these drugs have a low hydrosolubility, limiting clinical applications. Therefore, we used pH-sensitive polymeri...

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Detalles Bibliográficos
Autores principales: Jo, Min Jeong, Shin, Hee Ji, Yoon, Moon Sup, Kim, Seo Yeon, Jin, Chae Eun, Park, Chun-Woong, Kim, Jin-Seok, Shin, Dae Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866473/
https://www.ncbi.nlm.nih.gov/pubmed/36678783
http://dx.doi.org/10.3390/pharmaceutics15010154