CDT of Clostridioides difficile Induces MLC-Dependent Intestinal Barrier Dysfunction in HT-29/B6 Epithelial Cell Monolayers

Background: Clostridioides difficile binary toxin (CDT) defines the hypervirulence of strains in nosocomial antibiotic-induced colitis with the highest mortality. The objective of our study was to investigate the impact of CDT on the intestinal epithelial barrier and to enlighten the underlying mole...

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Detalles Bibliográficos
Autores principales: Heils, Lucas, Schneemann, Martina, Gerhard, Ralf, Schulzke, Jörg-Dieter, Bücker, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866553/
https://www.ncbi.nlm.nih.gov/pubmed/36668874
http://dx.doi.org/10.3390/toxins15010054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866553/
https://www.ncbi.nlm.nih.gov/pubmed/36668874
http://dx.doi.org/10.3390/toxins15010054

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