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Amphotericin B Nano-Assemblies Circumvent Intrinsic Toxicity and Ensure Superior Protection in Experimental Visceral Leishmaniasis with Feeble Toxic Manifestation

In spite of its high effectiveness in the treatment of both leishmaniasis as well as a range of fungal infections, the free form of the polyene antibiotic amphotericin B (AmB) does not entertain the status of the most preferred drug of choice in clinical settings. The high intrinsic toxicity of the...

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Detalles Bibliográficos
Autores principales: Jamal, Fauzia, Altaf, Ishrat, Ahmed, Ghufran, Asad, Sheikh, Ahmad, Hira, Zia, Qamar, Azhar, Asim, Farheen, Saba, Shafi, Taj, Karim, Shabana, Zubair, Swaleha, Owais, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866558/
https://www.ncbi.nlm.nih.gov/pubmed/36679946
http://dx.doi.org/10.3390/vaccines11010100