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Proteomic Analysis of Dupuytren’s Contracture-Derived Sweat Glands Revealed the Synthesis of Connective Tissue Growth Factor and Initiation of Epithelial-Mesenchymal Transition as Major Pathogenetic Events

Dupuytren’s contracture (DC) is a chronic and progressive fibroproliferative disorder restricted to the palmar fascia of the hands. Previously, we discovered the presence of high levels of connective tissue growth factor in sweat glands in the vicinity of DC nodules and hypothesized that sweat gland...

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Detalles Bibliográficos
Autores principales: Cárdenas-León, Claudia Griselda, Mäemets-Allas, Kristina, Klaas, Mariliis, Maasalu, Katre, Jaks, Viljar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866571/
https://www.ncbi.nlm.nih.gov/pubmed/36674597
http://dx.doi.org/10.3390/ijms24021081