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Proteomic Analysis of Dupuytren’s Contracture-Derived Sweat Glands Revealed the Synthesis of Connective Tissue Growth Factor and Initiation of Epithelial-Mesenchymal Transition as Major Pathogenetic Events
Dupuytren’s contracture (DC) is a chronic and progressive fibroproliferative disorder restricted to the palmar fascia of the hands. Previously, we discovered the presence of high levels of connective tissue growth factor in sweat glands in the vicinity of DC nodules and hypothesized that sweat gland...
Autores principales: | Cárdenas-León, Claudia Griselda, Mäemets-Allas, Kristina, Klaas, Mariliis, Maasalu, Katre, Jaks, Viljar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866571/ https://www.ncbi.nlm.nih.gov/pubmed/36674597 http://dx.doi.org/10.3390/ijms24021081 |
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