Novel 7-Chloro-4-aminoquinoline-benzimidazole Hybrids as Inhibitors of Cancer Cells Growth: Synthesis, Antiproliferative Activity, in Silico ADME Predictions, and Docking

In this study, new 7-chloro-4-aminoquinoline-benzimidazole compounds were synthesized and characterized by NMR, MS, and elemental analysis. These novel hybrids differ in the type of linker and in the substituent on the benzimidazole moiety. Their antiproliferative activities were evaluated on one no...

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Detalles Bibliográficos
Autores principales: Krstulović, Luka, Leventić, Marijana, Rastija, Vesna, Starčević, Kristina, Jirouš, Maja, Janić, Ivana, Karnaš, Maja, Lasić, Kornelija, Bajić, Miroslav, Glavaš-Obrovac, Ljubica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866588/
https://www.ncbi.nlm.nih.gov/pubmed/36677600
http://dx.doi.org/10.3390/molecules28020540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866588/
https://www.ncbi.nlm.nih.gov/pubmed/36677600
http://dx.doi.org/10.3390/molecules28020540

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