Synthesis, Biological Evaluation and Molecular Modeling Studies of Naphthoquinone Sulfonamides and Sulfonate Ester Derivatives as P2X7 Inhibitors

ATP acts in the extracellular environment as an important signal, activating a family of receptors called purinergic receptors. In recent years, interest in the potential therapeutics of purinergic components, including agonists and antagonists of receptors, has increased. Currently, many observatio...

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Detalles Bibliográficos
Autores principales: Pacheco, Paulo Anastácio Furtado, Gonzaga, Daniel Tadeu Gomes, von Ranke, Natalia Lidmar, Rodrigues, Carlos Rangel, da Rocha, David Rodrigues, da Silva, Fernando de Carvalho, Ferreira, Vitor Francisco, Faria, Robson Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866630/
https://www.ncbi.nlm.nih.gov/pubmed/36677652
http://dx.doi.org/10.3390/molecules28020590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866630/
https://www.ncbi.nlm.nih.gov/pubmed/36677652
http://dx.doi.org/10.3390/molecules28020590

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