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PD-L2 Blockade Exacerbates Liver Lesion in Mice Infected with Capillaria hepatica through Reducing Alternatively Activated Macrophages

Capillaria hepatica is a seriously neglected zoonotic parasite, which infects the liver of mammalian hosts, causing fibrosis or even hepatic failure. At present, the immune responses elicited by C. hepatica are not fully understood, and the role(s) of the programmed death 1 (PD-1) signaling pathway...

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Detalles Bibliográficos
Autores principales: Huang, Minjun, Li, Xiaoli, Zheng, Xiaoyan, Wang, Fei, Zou, Yang, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866821/
https://www.ncbi.nlm.nih.gov/pubmed/36668953
http://dx.doi.org/10.3390/tropicalmed8010046