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Identification of Structural Determinants of the Transport of the Dehydroascorbic Acid Mediated by Glucose Transport GLUT1

GLUT1 is a facilitative glucose transporter that can transport oxidized vitamin C (i.e., dehydroascorbic acid) and complements the action of reduced vitamin C transporters. To identify the residues involved in human GLUT1’s transport of dehydroascorbic acid, we performed docking studies in the 5 Å g...

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Detalles Bibliográficos
Autores principales: Villagrán, Marcelo, Burgos, Carlos F., Rivas, Coralia I., Mardones, Lorena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867014/
https://www.ncbi.nlm.nih.gov/pubmed/36677580
http://dx.doi.org/10.3390/molecules28020521