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Performance Comparison of Recombinant Baculovirus and Rabies Virus-like Particles production Using Two Culture Platforms

This work aimed to assess, following upstream optimization in Schott flasks, the scalability from this culture platform to a stirred-tank bioreactor in order to yield rabies-recombinant baculovirus, bearing genes of G (BVG) and M (BVM) proteins, and to obtain rabies virus-like particles (VLP) from t...

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Detalles Bibliográficos
Autores principales: Guardalini, Luis Giovani Oliveira, Cavalcante, Paulo Eduardo da Silva, Leme, Jaci, de Mello, Renata Gois, Bernardino, Thaissa Consoni, Jared, Simone Gonçalves Silva, Antoniazzi, Marta Maria, Astray, Renato Mancini, Tonso, Aldo, Fernández Núñez, Eutimio Gustavo, Jorge, Soraia Attie Calil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867115/
https://www.ncbi.nlm.nih.gov/pubmed/36679884
http://dx.doi.org/10.3390/vaccines11010039