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Lipophilicity and ADMET Analysis of Quinoline-1,4-quinone Hybrids

Lipophilicity is one of the basic properties of a potential drug determining its solubility in non-polar solvents and, consequently, its ability to passively penetrate the cell membrane, as well as the occurrence of various pharmacokinetic processes, including adsorption, distribution, metabolism, e...

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Detalles Bibliográficos
Autores principales: Kadela-Tomanek, Monika, Jastrzębska, Maria, Chrobak, Elwira, Bębenek, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867208/
https://www.ncbi.nlm.nih.gov/pubmed/36678664
http://dx.doi.org/10.3390/pharmaceutics15010034