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Development and Preliminary Application of a Droplet Digital PCR Assay for Quantifying the Oncolytic Herpes Simplex Virus Type 1 in the Clinical-Grade Production

Oncolytic herpes simplex virus (oHSV) is a type of virus that selectively targets and kills cancer cells, leaving normal cells unharmed. Accurate viral titer is of great importance for the production and application of oHSV products. Droplet digital PCR (ddPCR) is known for having good reproducibili...

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Detalles Bibliográficos
Autores principales: Guo, Miaomiao, Deng, Li, Liang, Hongyang, Du, Yuyao, Gao, Wenrui, Tian, Na, Bi, Ying, Li, Jinghua, Ma, Tiancong, Zhang, Yuntao, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867280/
https://www.ncbi.nlm.nih.gov/pubmed/36680218
http://dx.doi.org/10.3390/v15010178