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Synthesis of Novel 1,3,4-Oxadiazole-Derived α-Aminophosphonates/α-Aminophosphonic Acids and Evaluation of Their In Vitro Antiviral Activity against the Avian Coronavirus Infectious Bronchitis Virus

An efficient and simple approach has been developed for the synthesis of eight dialkyl/aryl[(5-phenyl-1,3,4-oxadiazol-2-ylamino)(aryl)methyl]phosphonates through the Pudovik-type reaction of dialkyl/arylphosphite with imines, obtained from 5-phenyl-1,3,4-oxadiazol-2-amine and aromatic aldehydes, und...

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Detalles Bibliográficos
Autores principales: Hkiri, Shaima, Mekni-Toujani, Marwa, Üstün, Elvan, Hosni, Karim, Ghram, Abdeljelil, Touil, Soufiane, Samarat, Ali, Sémeril, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867332/
https://www.ncbi.nlm.nih.gov/pubmed/36678743
http://dx.doi.org/10.3390/pharmaceutics15010114