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Synthesis of Novel 1,3,4-Oxadiazole-Derived α-Aminophosphonates/α-Aminophosphonic Acids and Evaluation of Their In Vitro Antiviral Activity against the Avian Coronavirus Infectious Bronchitis Virus
An efficient and simple approach has been developed for the synthesis of eight dialkyl/aryl[(5-phenyl-1,3,4-oxadiazol-2-ylamino)(aryl)methyl]phosphonates through the Pudovik-type reaction of dialkyl/arylphosphite with imines, obtained from 5-phenyl-1,3,4-oxadiazol-2-amine and aromatic aldehydes, und...
Autores principales: | Hkiri, Shaima, Mekni-Toujani, Marwa, Üstün, Elvan, Hosni, Karim, Ghram, Abdeljelil, Touil, Soufiane, Samarat, Ali, Sémeril, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867332/ https://www.ncbi.nlm.nih.gov/pubmed/36678743 http://dx.doi.org/10.3390/pharmaceutics15010114 |
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