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Synthesis of Dihydropyrimidines: Isosteres of Nifedipine and Evaluation of Their Calcium Channel Blocking Efficiency

Hypertension and cardiovascular diseases related to it remain the leading medical challenges globally. Several drugs have been synthesized and commercialized to manage hypertension. Some of these drugs have a dihydropyrimidine skeleton structure, act as efficient calcium channel blockers, and affect...

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Detalles Bibliográficos
Autores principales: Zohny, Yasser M., Awad, Samir M., Rabie, Maha A., Al-Saidan, Omar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867414/
https://www.ncbi.nlm.nih.gov/pubmed/36677842
http://dx.doi.org/10.3390/molecules28020784