Cargando…
Synthesis of Dihydropyrimidines: Isosteres of Nifedipine and Evaluation of Their Calcium Channel Blocking Efficiency
Hypertension and cardiovascular diseases related to it remain the leading medical challenges globally. Several drugs have been synthesized and commercialized to manage hypertension. Some of these drugs have a dihydropyrimidine skeleton structure, act as efficient calcium channel blockers, and affect...
Autores principales: | Zohny, Yasser M., Awad, Samir M., Rabie, Maha A., Al-Saidan, Omar A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867414/ https://www.ncbi.nlm.nih.gov/pubmed/36677842 http://dx.doi.org/10.3390/molecules28020784 |
Ejemplares similares
-
Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Pyrimidine Derivatives as Potential Calcium Channel Blockers
por: Zohny, Yasser M., et al.
Publicado: (2023) -
Calcium channel blocking activity of a dihydropyrimidine derivative (BKVIII) on rabbit's aortic strip
por: Kumar, Rakesh, et al.
Publicado: (2013) -
New mechanisms of antiplatelet activity of nifedipine, an L-type calcium channel blocker
por: Chou, Tz-Chong
Publicado: (2014) -
Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Thiouracil Derivatives as Potential Antithyroid Agents
por: Awad, Samir M., et al.
Publicado: (2018) -
N-Edited
Guanine Isosteres
por: Li, Xin, et al.
Publicado: (2023)