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Development of Inhalable Spray Dried Nitrofurantoin Formulations for the Treatment of Emphysema

A central characteristic of emphysematous progression is the continuous destruction of the lung extracellular matrix (ECM). Current treatments for emphysema have only addressed symptoms rather than preventing or reversing the loss of lung ECM. Nitrofurantoin (NF) is an antibiotic that has the potent...

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Detalles Bibliográficos
Autores principales: Leslie, Mathew N., Marasini, Nirmal, Sheikh, Zara, Young, Paul M., Traini, Daniela, Ong, Hui Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867496/
https://www.ncbi.nlm.nih.gov/pubmed/36678775
http://dx.doi.org/10.3390/pharmaceutics15010146