Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing

Emerging advances in the field of in vitro toxicity testing attempt to meet the need for reliable human-based safety assessment in drug development. Intrahepatic cholangiocyte organoids (ICOs) are described as a donor-derived in vitro model for disease modelling and regenerative medicine. Here, we e...

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Detalles Bibliográficos
Autores principales: Bouwmeester, Manon C., Tao, Yu, Proença, Susana, van Steenbeek, Frank G., Samsom, Roos-Anne, Nijmeijer, Sandra M., Sinnige, Theo, van der Laan, Luc J. W., Legler, Juliette, Schneeberger, Kerstin, Kramer, Nynke I., Spee, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867526/
https://www.ncbi.nlm.nih.gov/pubmed/36677681
http://dx.doi.org/10.3390/molecules28020621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867526/
https://www.ncbi.nlm.nih.gov/pubmed/36677681
http://dx.doi.org/10.3390/molecules28020621

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