Single-cell RNA binding protein regulatory network analyses reveal oncogenic HNRNPK-MYC signalling pathway in cancer

RNA-binding proteins (RBPs) are key players of gene expression and perturbations of RBP-RNA regulatory network have been observed in various cancer types. Here, we propose a computational method, RBPreg, to identify the RBP regulators by integration of single cell RNA-Seq (N = 233,591) and RBP bindi...

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Detalles Bibliográficos
Autores principales: Zhou, Weiwei, Jie, Qiuling, Pan, Tao, Shi, Jingyi, Jiang, Tiantongfei, Zhang, Ya, Ding, Na, Xu, Juan, Ma, Yanlin, Li, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867709/
https://www.ncbi.nlm.nih.gov/pubmed/36681772
http://dx.doi.org/10.1038/s42003-023-04457-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867709/
https://www.ncbi.nlm.nih.gov/pubmed/36681772
http://dx.doi.org/10.1038/s42003-023-04457-2

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