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Therapeutic beta-lactam dosages and broad-spectrum antibiotics are associated with reductions in microbial richness and diversity in persons with cystic fibrosis

Persons with cystic fibrosis (PwCF) suffer from pulmonary exacerbations (PEx) related in part to lung infection. While higher microbial diversity is associated with higher lung function, the data on the impact of short-term antibiotics on changes in microbial diversity is conflicting. Further, Prevo...

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Detalles Bibliográficos
Autores principales: Hahn, Andrea, Burrell, Aszia, Chaney, Hollis, Sami, Iman, Koumbourlis, Anastassios C., Freishtat, Robert J., Crandall, Keith A., Zemanick, Edith T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867719/
https://www.ncbi.nlm.nih.gov/pubmed/36681756
http://dx.doi.org/10.1038/s41598-023-27628-x