Epigenomic charting and functional annotation of risk loci in renal cell carcinoma

While the mutational and transcriptional landscapes of renal cell carcinoma (RCC) are well-known, the epigenome is poorly understood. We characterize the epigenome of clear cell (ccRCC), papillary (pRCC), and chromophobe RCC (chRCC) by using ChIP-seq, ATAC-Seq, RNA-seq, and SNP arrays. We integrate...

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Detalles Bibliográficos
Autores principales: Nassar, Amin H., Abou Alaiwi, Sarah, Baca, Sylvan C., Adib, Elio, Corona, Rosario I., Seo, Ji-Heui, Fonseca, Marcos A. S., Spisak, Sandor, El Zarif, Talal, Tisza, Viktoria, Braun, David A., Du, Heng, He, Monica, Flaifel, Abdallah, Alchoueiry, Michel, Denize, Thomas, Matar, Sayed G., Acosta, Andres, Shukla, Sachet, Hou, Yue, Steinharter, John, Bouchard, Gabrielle, Berchuck, Jacob E., O’Connor, Edward, Bell, Connor, Nuzzo, Pier Vitale, Mary Lee, Gwo-Shu, Signoretti, Sabina, Hirsch, Michelle S., Pomerantz, Mark, Henske, Elizabeth, Gusev, Alexander, Lawrenson, Kate, Choueiri, Toni K., Kwiatkowski, David J., Freedman, Matthew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867739/
https://www.ncbi.nlm.nih.gov/pubmed/36681680
http://dx.doi.org/10.1038/s41467-023-35833-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867739/
https://www.ncbi.nlm.nih.gov/pubmed/36681680
http://dx.doi.org/10.1038/s41467-023-35833-5

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