A proteome scale study reveals how plastic surfaces and agitation promote protein aggregation

Protein aggregation in biotherapeutics can reduce their activity and effectiveness. It may also promote immune reactions responsible for severe adverse effects. The impact of plastic materials on protein destabilization is not totally understood. Here, we propose to deconvolve the effects of materia...

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Detalles Bibliográficos
Autores principales: Schvartz, Marion, Saudrais, Florent, Devineau, Stéphanie, Aude, Jean-Christophe, Chédin, Stéphane, Henry, Céline, Millán-Oropeza, Aarón, Perrault, Thomas, Pieri, Laura, Pin, Serge, Boulard, Yves, Brotons, Guillaume, Renault, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867740/
https://www.ncbi.nlm.nih.gov/pubmed/36681766
http://dx.doi.org/10.1038/s41598-023-28412-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867740/
https://www.ncbi.nlm.nih.gov/pubmed/36681766
http://dx.doi.org/10.1038/s41598-023-28412-7

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