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A proteome scale study reveals how plastic surfaces and agitation promote protein aggregation
Protein aggregation in biotherapeutics can reduce their activity and effectiveness. It may also promote immune reactions responsible for severe adverse effects. The impact of plastic materials on protein destabilization is not totally understood. Here, we propose to deconvolve the effects of materia...
Autores principales: | Schvartz, Marion, Saudrais, Florent, Devineau, Stéphanie, Aude, Jean-Christophe, Chédin, Stéphane, Henry, Céline, Millán-Oropeza, Aarón, Perrault, Thomas, Pieri, Laura, Pin, Serge, Boulard, Yves, Brotons, Guillaume, Renault, Jean-Philippe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867740/ https://www.ncbi.nlm.nih.gov/pubmed/36681766 http://dx.doi.org/10.1038/s41598-023-28412-7 |
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