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A microfluidic-based PDAC organoid system reveals the impact of hypoxia in response to treatment

Pancreatic Ductal Adenocarcinoma (PDAC) is estimated to become the second leading cause of cancer-related deaths by 2030 with mortality rates of up to 93%. Standard of care chemotherapeutic treatment only prolongs the survival of patients for a short timeframe. Therefore, it is important to understa...

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Detalles Bibliográficos
Autores principales: Geyer, Marlene, Schreyer, Daniel, Gaul, Lisa-Marie, Pfeffer, Susanne, Pilarsky, Christian, Queiroz, Karla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867742/
https://www.ncbi.nlm.nih.gov/pubmed/36681673
http://dx.doi.org/10.1038/s41420-023-01334-z