DNA damage triggers squamous metaplasia in human lung and mammary cells via mitotic checkpoints

Epithelial transdifferentiation is frequent in tissue hyperplasia and contributes to disease in various degrees. Squamous metaplasia (SQM) precedes epidermoid lung cancer, an aggressive and frequent malignancy, but it is rare in the epithelium of the mammary gland. The mechanisms leading to SQM in t...

Descripción completa

Detalles Bibliográficos
Autores principales: Juan, Lucía San, Freije, Ana, Sanz-Gómez, Natalia, Jiménez-Matías, Beatriz, Pleguezuelos-Manzano, Cayetano, Sanz, J. Ramón, de Diego, Ernesto, Naranjo, Sara, Clevers, Hans, Gandarillas, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867756/
https://www.ncbi.nlm.nih.gov/pubmed/36681661
http://dx.doi.org/10.1038/s41420-023-01330-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867756/
https://www.ncbi.nlm.nih.gov/pubmed/36681661
http://dx.doi.org/10.1038/s41420-023-01330-3

Ejemplares similares