Tailless and hypoxia inducible factor-2α cooperate to sustain proangiogenic states of retinal astrocytes in neonatal mice

Tailless (TLX, an orphan nuclear receptor) and hypoxia inducible factor-2α (HIF2α) are both essential for retinal astrocyte and vascular development. Tlx(−/−) mutation and astrocyte specific Hif2α disruption in Hif2α(f/f)/GFAPCre mice are known to cause defective astrocyte development and block vasc...

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Detalles Bibliográficos
Autores principales: Duan, Li-Juan, Jiang, Yida, Shi, Yanhong, Fong, Guo-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867894/
https://www.ncbi.nlm.nih.gov/pubmed/36625299
http://dx.doi.org/10.1242/bio.059684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867894/
https://www.ncbi.nlm.nih.gov/pubmed/36625299
http://dx.doi.org/10.1242/bio.059684

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