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Tailless and hypoxia inducible factor-2α cooperate to sustain proangiogenic states of retinal astrocytes in neonatal mice
Tailless (TLX, an orphan nuclear receptor) and hypoxia inducible factor-2α (HIF2α) are both essential for retinal astrocyte and vascular development. Tlx(−/−) mutation and astrocyte specific Hif2α disruption in Hif2α(f/f)/GFAPCre mice are known to cause defective astrocyte development and block vasc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867894/ https://www.ncbi.nlm.nih.gov/pubmed/36625299 http://dx.doi.org/10.1242/bio.059684 |