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Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice

Hem1 (hematopoietic protein 1), a hematopoietic cell–specific member of the Hem family of cytoplasmic adaptor proteins, is essential for lymphopoiesis and innate immunity as well as for the transition of hematopoiesis from the fetal liver to the bone marrow. However, the role of Hem1 in bone cell di...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyan, Shao, Lijian, Richardson, Kimberly K., Ling, Wen, Warren, Aaron, Krager, Kimberly, Aykin-Burns, Nukhet, Hromas, Robert, Zhou, Daohong, Almeida, Maria, Kim, Ha-Neui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9867982/
https://www.ncbi.nlm.nih.gov/pubmed/36574841
http://dx.doi.org/10.1016/j.jbc.2022.102841