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Stemness‐related genes revealed by single‐cell profiling of naïve and stimulated human CD34(+) cells from CB and mPB
BACKGROUND: Hematopoietic stem cells (HSCs) from different sources show varied repopulating capacity, and HSCs lose their stemness after long‐time ex vivo culture. A deep understanding of these phenomena may provide helpful insights for HSCs. METHODS: Here, we applied single‐cell RNA‐seq (scRNA‐seq)...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868212/ https://www.ncbi.nlm.nih.gov/pubmed/36683248 http://dx.doi.org/10.1002/ctm2.1175 |