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Stemness‐related genes revealed by single‐cell profiling of naïve and stimulated human CD34(+) cells from CB and mPB

BACKGROUND: Hematopoietic stem cells (HSCs) from different sources show varied repopulating capacity, and HSCs lose their stemness after long‐time ex vivo culture. A deep understanding of these phenomena may provide helpful insights for HSCs. METHODS: Here, we applied single‐cell RNA‐seq (scRNA‐seq)...

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Detalles Bibliográficos
Autores principales: Dong, Guoyi, Xu, Xiaojing, Li, Yue, Ouyang, Wenjie, Zhao, Weihua, Gu, Ying, Li, Jie, Liu, Tianbin, Zeng, Xinru, Zou, Huilin, Wang, Shuguang, Chen, Yue, Liu, Sixi, Sun, Hai‐Xi, Liu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868212/
https://www.ncbi.nlm.nih.gov/pubmed/36683248
http://dx.doi.org/10.1002/ctm2.1175