Malvidin alleviates mitochondrial dysfunction and ROS accumulation through activating AMPK-α/UCP2 axis, thereby resisting inflammation and apoptosis in SAE mice

This study aimed to explore the protective roles of malvidin in life-threatened sepsis-associated encephalopathy (SAE) and illustrate the underlying mechanism. SAE mice models were developed and treated with malvidin for subsequently protective effects evaluation. Malvidin restored neurobehavioral r...

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Detalles Bibliográficos
Autores principales: Zhao, Panpan, Li, Xiaomin, Yang, Qiankun, Lu, Yingzhi, Wang, Guanglu, Yang, Haitao, Dong, Jingquan, Zhang, Honggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868257/
https://www.ncbi.nlm.nih.gov/pubmed/36699054
http://dx.doi.org/10.3389/fphar.2022.1038802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868257/
https://www.ncbi.nlm.nih.gov/pubmed/36699054
http://dx.doi.org/10.3389/fphar.2022.1038802

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