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Deciphering the mechanism of Tinospora cordifolia extract on Th17 cells through in-depth transcriptomic profiling and in silico analysis

Naive CD4(+) T cells differentiate into effector (Th1, Th2, Th17) cells and immunosuppressive (Treg) cells upon antigenic stimulation in the presence of a specific cytokine milieu. The T cell in vitro culture system provides a very efficient model to study compounds’ therapeutic activity and mechani...

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Detalles Bibliográficos
Autores principales: Nandan, Amrita, Sharma, Vishwas, Banerjee, Prodyot, Sadasivam, Kannan, Venkatesan, Subramanian, Prasher, Bhavana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868420/
https://www.ncbi.nlm.nih.gov/pubmed/36699055
http://dx.doi.org/10.3389/fphar.2022.1056677