Purinoreceptors and ectonucleotidases control ATP-induced calcium waveforms and calcium-dependent responses in microglia: Roles of P2 receptors and CD39 in ATP-stimulated microglia

Adenosine triphosphate (ATP) and its metabolites drive microglia migration and cytokine production by activating P2X- and P2Y- class purinergic receptors. Purinergic receptor activation gives rise to diverse intracellular calcium (Ca2+ signals, or waveforms, that differ in amplitude, duration, and f...

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Detalles Bibliográficos
Autores principales: Chun, Byeong J., Aryal, Surya P., Varughese, Peter, Sun, Bin, Bruno, Joshua A., Richards, Chris I., Bachstetter, Adam D., Kekenes-Huskey, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868579/
https://www.ncbi.nlm.nih.gov/pubmed/36699679
http://dx.doi.org/10.3389/fphys.2022.1037417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868579/
https://www.ncbi.nlm.nih.gov/pubmed/36699679
http://dx.doi.org/10.3389/fphys.2022.1037417

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