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Purinoreceptors and ectonucleotidases control ATP-induced calcium waveforms and calcium-dependent responses in microglia: Roles of P2 receptors and CD39 in ATP-stimulated microglia
Adenosine triphosphate (ATP) and its metabolites drive microglia migration and cytokine production by activating P2X- and P2Y- class purinergic receptors. Purinergic receptor activation gives rise to diverse intracellular calcium (Ca2+ signals, or waveforms, that differ in amplitude, duration, and f...
Autores principales: | Chun, Byeong J., Aryal, Surya P., Varughese, Peter, Sun, Bin, Bruno, Joshua A., Richards, Chris I., Bachstetter, Adam D., Kekenes-Huskey, Peter M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868579/ https://www.ncbi.nlm.nih.gov/pubmed/36699679 http://dx.doi.org/10.3389/fphys.2022.1037417 |
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